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Garlic Mayo Glazed Turkey Breast

this post is sponsored by Duke’s Mayonnaise—all opinions are my own

Garlic Mayo Glazed Turkey Breast is an impossibly simple, moist, and tender turkey breast recipe you need for your Thanksgiving dinner.

Garlic Mayo Glazed Turkey Breast

Garlic Mayo Glazed Turkey Breast may sound crazy, and totally untraditional, but it’s about to become your tradition.

The garlic-infused Duke’s Mayonnaise adds a pungent and nutty flavor to your turkey breast while keeping it incredibly *moist* and tender.

Now y’all, let’s chat a minute about mayonnaise.

If you’re from the South, Duke’s Mayonnaise is a religion. There is no other mayo on a southern belle’s shelf—it’s a family staple that has a deep southern heritage.

One of my favorite sounds was the sound of my grandmother making me a sandwich and spreading Duke’s on the bread slices—hearing her knife go in and out of the glass jar… Y’all. It almost makes my eyes well up with tears thinking about how I haven’t heard that sound in many years.

That yellow and red label is undeniable and you’ll love its tangy flavor, no sugar (which means it’s perfect for my keto/low carb friends!), and the fact that it’s a brand trusted by professional chefs and home cooks alike. 

If your store doesn’t sell this delicacy, you can order from their website, or on Amazon.

Do y’all know all the ways you can use Duke’s, not just in a sandwich?!

Follow their social media to learn ALL.THE.WAYS people pay homage to this real mayonnaise.

Thanksgiving Roasted Turkey with Lemon and Herbs

Alright, so it’s Thanksgiving, you need to make a turkey, but you don’t need a big one.

This year, we’re doing split turkey breasts, since it’s just a handful of us.

You can read all about Grandma’s Roasted Turkey—which is our traditional turkey recipe.

But, 2020 is quite short on tradition.

Here are my tips for choosing a turkey:

  • Bigger isn’t better. The bigger your turkey, the longer you’ll need to roast it, which means the more chance you have for error. You’re better off buying two smaller 12-13 pound birds and roasting them, than a giant 24 pounder.
  • With a smaller bird, the cooking time is less. This means more time for the “oven swap” game when you have other casseroles to bake! Woo hoo!
  • Choose a turkey with four ingredients or less on the label. And you may be asking “what the heck, isn’t it just turkey?!” Not always! Lots of fillers and injections for plumping up your turkey… be kind to yourself and get the least amount of ingredients in your turkey! 
  • You don’t have to brine your turkey. Especially if you’re slathering it in mayonnaise, the skin will get wonderfully crisp, and juicy tender inside.
  • Use an instant-read meat thermometer. And cook your turkey until 165˚.
  • Let it rest! This might be the most important step… let your bird set on your counter for a good 20+ minutes allowing the bird to relax and the juices to settle back into the bird.

Mayo Glazed Split Turkey Breast

Now, let’s talk Garlic Mayo Glazed Turkey Breast—

This is about the easiest glaze you’ve ever made in your life.

No cooking, just chop, stir, and slather!

I highly recommend saving a little bowl for dipping later… Just sayin’!

And using mayo helps keep your turkey *moist* making it almost impossible to overcook.

This is exactly the palate-thrilling, bold move you need to make this Thanksgiving!

Here’s a quick overview of how to make Garlic Mayo Glazed Turkey Breast

  1. Stir grated garlic, lemon zest, and juice, chopped herbs, salt, pepper, and mayo together in a bowl. 
  2. Slather this glaze all over your turkey breasts.
  3. Roast at 425˚ for about an hour.
  4. During the last 20 minutes, glaze your turkey every 5 minutes.

Turkey Breast with Garlic Mayo Glaze

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Here are some questions you might have while roasting your turkey breast:


How do you know when your turkey breast is done? 

When an instant-read thermometer reads 165˚.

What temperature should I cook a turkey breast?

I prefer a higher roasting temperature of 425˚, but 350˚ is also a great temperature to roast your bird. You’ll need a bit longer on the cooking time, though.

How do I keep the turkey moist?

Well, start with a mayo glaze! ?  In all seriousness, basting during the last 20 minutes of cooking does help keep moisture in turkey. 

Full Turkey Dinner

Finally, after 15 minutes of resting carve your turkey breast up, and serve with all your favorite Thanksgiving sides. 

Garlic Mayo Turkey Glaze

You best believe I saved a dipping cup with the Garlic Mayo Glaze in it!

Dipping Turkey in to Garlic Mayo

Lastly, need some Thanksgiving Side Dish Recipes or Tips?

Side Dish Recipe Ideas:

Save this recipe to your favorite Thanksgiving recipe board!

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Thanksgiving Turkey for Four People

Garlic Mayo Glazed Turkey Breast

5 from 6 reviews
  • Author: Sweetpea
  • Prep Time: 15
  • Cook Time: 60
  • Total Time: 1 hour 15 minutes
  • Yield: 4 1x
  • Category: main dish
  • Method: oven-baked
  • Cuisine: Thanksgiving


Garlic Mayo Glazed Turkey Breast is an impossibly simple, moist, and tender turkey breast recipe you need for your Thanksgiving dinner


  • 2 Split Turkey Breast
  • 1 cup Duke’s Real Mayonnaise
  • 4 garlic cloves, grated
  • 1 lemon, zested & juiced
  • 1 tsp minced fresh sage
  • 1 tsp minced fresh thyme
  • 1 tsp minced fresh rosemary
  • 1 tsp salt
  • 1 tsp pepper


  1. Preheat your oven to 425˚.
  2. In a mixing bowl, combine Duke’s Real Mayonnaise with garlic, lemon zest & juice, herbs, salt, and pepper.
  3. Stir this really well.
  4. Take your split turkey breasts, and slather all sides with the mayo glaze.
  5. Place in a roasting pan, and roast at 425˚ for 45 minutes to an hour, or until the internal temperature is 165˚.
  6. During the last 20 minutes of cooking, glaze to turkey every 5 minutes with the mayo glaze.
  7. Allow resting for 15 minutes before slicing and serving.

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So, how do you use mayonnaise outside of a sandwich?! Tell me in the comments below!

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  1. The turkey breast to fight for! 🙂 Love how moist this turkey looks – even the pictures make my mouth water!

    1. Sarah!! Thank you for coming back to comment this! Y’all enjoy round two, we’re doing the same thing! Happy Christmas!

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